隐性脊柱神经管闭合不全患儿的皮肤表现:54例病例回顾

更新时间:2023-06-14

【摘要】Objectives: To verify the diagnostic value of lumbosacral midline cutaneous lesions in asymptomatic children to detect occult spinal dysraphism(OSD)and to propose a practical approach for clinical investigations with respect to the type of cutaneous lesions observed. Design: Retrospective study of 54 children referred to the Department of Pediatric Dermatology between 1990 and 1999 for congenital midline lumbosacral cutaneous lesions. Setting: The private or institutional practices of participating dermatologists and pediatricians. Main Outcome Measures: Evaluation of the diagnostic value of midline cutaneous lesions for the detection of OSD. Association of skin examination findings with spinal anomalies detected by magnetic resonance imaging or ultrasound. Results: Occult spinal dysraphism was detected in 3 of 36 patients with an isolated congenital midline lesion and 11 of 18 patients with a combination of 2 or more different skin lesions. Conclusions: A combination of 2 or more congenital midline skin lesions is the strongest marker of OSD. Careful dermatologic examination is needed to detect suggestive markers and request a spinal magnetic resonance image, which is the most sensitive radiologic approach to detect an OSD.

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